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William Hornebeck Selected Research

elastin-binding proteins

9/2009Role of the elastin receptor complex (S-Gal/Cath-A/Neu-1) in skin repair and regeneration.
4/2005Elastin peptides activate extracellular signal-regulated kinase 1/2 via a Ras-independent mechanism requiring both p110gamma/Raf-1 and protein kinase A/B-Raf signaling in human skin fibroblasts.
2/2004Elastin-derived peptides upregulate matrix metalloproteinase-2-mediated melanoma cell invasion through elastin-binding protein.
1/2002Cumulative influence of elastin peptides and plasminogen on matrix metalloproteinase activation and type I collagen invasion by HT-1080 fibrosarcoma cells.

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William Hornebeck Research Topics

Disease

16Neoplasms (Cancer)
06/2009 - 06/2002
9Melanoma (Melanoma, Malignant)
06/2009 - 06/2002
2Fibrosarcoma
02/2008 - 01/2002
2Necrosis
07/2007 - 05/2002
2Pathologic Processes
06/2003 - 01/2003
1Atherosclerosis
08/2013
1Chronic Obstructive Pulmonary Disease (COPD)
07/2012
1Lung Neoplasms (Lung Cancer)
07/2012
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2012
1Wounds and Injuries (Trauma)
09/2009
1Ischemia
07/2007
1Reperfusion Injury
07/2007
1Colorectal Neoplasms (Colorectal Cancer)
01/2007
1Microsatellite Instability
01/2007
1Erythema
12/2005
1Osteosarcoma (Osteogenic Sarcoma)
03/2005
1Virus Diseases (Viral Diseases)
03/2005
1Vascular Diseases (Vascular Disease)
02/2004

Drug/Important Bio-Agent (IBA)

13Matrix Metalloproteinases (MMPs)IBA
01/2007 - 01/2002
9ElastinIBA
08/2013 - 01/2002
8Peptides (Polypeptides)IBA
09/2009 - 01/2002
7Matrix Metalloproteinase 2 (Gelatinase A)IBA
06/2009 - 11/2003
5cyclohexenoesculetin-beta-galactoside (S-Gal)IBA
07/2007 - 06/2002
5Metalloproteases (Metalloproteinases)IBA
01/2007 - 06/2003
5Peptide Hydrolases (Proteases)FDA Link
12/2004 - 06/2002
4elastin-binding proteinsIBA
09/2009 - 01/2002
4CytokinesIBA
11/2007 - 11/2003
4Collagen Type I (Type I Collagen)IBA
07/2005 - 01/2002
3CollagenIBA
06/2009 - 03/2004
3collagenase 1IBA
06/2009 - 07/2003
3Matrix Metalloproteinase 14 (MT1-MMP)IBA
01/2007 - 06/2002
3FibrinolysinFDA Link
02/2004 - 01/2003
2Pancreatic Elastase (Elastase)IBA
08/2013 - 09/2009
2EnzymesIBA
02/2008 - 07/2003
2ThrombospondinsIBA
02/2008 - 12/2004
2Tissue Inhibitor of Metalloproteinase-1IBA
01/2007 - 03/2005
2Tissue Inhibitor of Metalloproteinase-2IBA
01/2007 - 11/2003
2Proteins (Proteins, Gene)FDA Link
12/2004 - 05/2002
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2004 - 11/2003
2PlasminogenIBA
11/2003 - 01/2002
1Leukocyte Elastase (Neutrophil Elastase)IBA
07/2012
1Collagenases (Collagenase)FDA Link
06/2009
1trichostatin A (A 300)IBA
10/2008
1N-acetylsphingosineIBA
10/2008
1Histones (Histone)IBA
10/2008
1Histone Deacetylase InhibitorsIBA
10/2008
1CeramidesIBA
10/2008
1Thrombospondin 1IBA
02/2008
1Phosphotransferases (Kinase)IBA
07/2007
1Creatine Kinase (Creatine Phosphokinase)IBA
07/2007
1Biological ProductsIBA
01/2007
1GelatinasesIBA
01/2007
1Transcription Factors (Transcription Factor)IBA
12/2005
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
03/2005
1DisintegrinsIBA
03/2005
1LDL Receptors (LDL Receptor)IBA
12/2004
1EndopeptidasesIBA
03/2004
1Matrix Metalloproteinase InhibitorsIBA
03/2004
1ZincIBA
03/2004
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
02/2004
1LactoseFDA LinkGeneric
02/2004
1beta-Galactosidase (Lactaid)IBA
02/2004
1Transforming Growth Factor beta (TGF-beta)IBA
11/2003
1Transforming Growth Factor beta1 (TGF beta 1)IBA
11/2003
1Matrix Metalloproteinase 3 (Stromelysin 1)IBA
07/2003
1estropipate (Ogen)FDA LinkGeneric
01/2003
1valyl-glycyl-valyl-alanyl-prolyl-glycineIBA
06/2002
1Collagen Type IV (Type IV Collagen)IBA
06/2002
1Integrin alphaVbeta3IBA
06/2002
1progelatinaseIBA
06/2002
1InterleukinsIBA
05/2002
1Interleukin-8 (Interleukin 8)IBA
05/2002
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2002
1Messenger RNA (mRNA)IBA
05/2002

Therapy/Procedure

1Therapeutics
03/2005
1Subcutaneous Injections
11/2003